Lawyer Overview

Julia Grimes is a technology specialist in the Intellectual Property Department at WilmerHale. She joined the firm in 2006.

Practice

Dr. Grimes' practice focuses on patent prosecution in all areas of biotechnology and the biomedical sciences. Prior to joining WilmerHale, she worked as a scientific advisor at another New York City law firm, where she gained experience in patent prosecution, patent invalidity and non-infringement opinions, freedom-to-operate analyses and due diligence studies.

Dr. Grimes spent two years working in technology transfer for the Medical Research Council, the UK equivalent of the National Institutes of Health, where she was responsible for procurement and licensing of the oncology, virology and neuroscience patent portfolios.

From 1996 to 2000, Dr. Grimes was a Howard Hughes Medical Institute post-doctoral fellow in the Department of Neurobiology at the State University of New York, Stony Brook. Her postdoctoral research focused on the regulation of gene expression in the nervous system. Dr. Grimes received her Ph.D. from Imperial College, London, where her thesis research involved the cell biology of cancer metastasis.

Publications

• Ding Y., Robbins J., Fraser S.P., Grimes JA, Djamgoz M.B., “Comparative studies of intracellular calcium in strongly and weakly metastatic rat prostate cancer cell lines,” International Journal of Biochemistry & Cell Biology 38, 366-375 (2006).
• Fraser, S.P., Grimes, J.A., Diss, J.K.J, Stewart, D., Dolly, D. O., & Djamgoz, M.B.A., “ Predominant expression of Kv1.3 voltage-gated K+ channel subunit in rat prostate cancer cell line: electrophysiological, pharmacological and molecular characterization,” European Journal of Physiology 446, 559-571 (2003).
• Grimes, J.A., Nielsen, S.J., Battaglioli, E., Miska, E.A., Speh, J.C., Berry, D.L., Atouf, F., Holdener, B.C., Mandel, G.   & Kouzarides, T., “The co-repressor mSin3A is a functional component of the REST/CoREST repressor complex,” Journal of Biological Chemistry 275, 9461-9467 (2000).
• Fraser, S.P., Grimes, J.A. & Djamgoz, M.B.A., “Effects of voltage-gated ion channel modulators on rat prostatic cancer cell proliferation: Comparison of highly and weakly metastatic cell lines,” Prostate 44,   61-76 (2000). 
• Andres, M.E., Burger, C., Peral-Rubio, M.J., Anderson, M.E., Grimes, J.A., Dallman, J., Ballas, N. & Mandel, G, “CoREST: A functional co-repressor required for regulation of neural-specific gene expression,” Proceedings of the National Academy of Sciences 96, 9873-9878 (1999).
• Grimes, J.A. & Djamgoz, M.B.A., “Electrophysiological characterization of a voltage-gated Na+ current expressed in the highly metastatic Mat-LyLu rat prostate cancer cell line,” Journal of Cellular Physiology 175, 50-58 (1998).
• Laniado, M.E., Lalani, E.N., Fraser, S.P., Grimes, J.A., Bhangal, G., Djamgoz, M.B.A. & Abel, P.D., “Expression and functional analysis of voltage-activated Na+ channels in human prostate cancer cell lines and their contribution to invasion in vitro,” American Journal of Pathology 150, 1213-1221 (1997).
• Grimes, J.A. & Djamgoz, M.B.A., “Voltage-gated K+ current in the highly metastatic MAT-LyLu rat prostate cancer cell line: Electrophysiological and pharmacological characteristics,” Journal of Physiology 495P, 76P (1996).
• Grimes, J.A., Fraser, S.P., Stephens, G.J., Downing, J.E.G., Laniado, M.E., Foster, C.S., Abel, P.D. & Djamgoz, M.B.A., “Differential expression of voltage-activated Na+ currents in two prostatic tumour cell lines: Contribution to invasiveness in vitro,” FEBS Letters 369, 290-294 (1995).
• Grimes, J.A. & Djamgoz, M.B.A., “Electrophysiological characterization of a TTX-sensitive Na+ current in the highly metastatic MAT-LyLu rat prostate cancer cell line,” Journal of Physiology 489P, 50P (1995).

Professional Activities

Dr. Grimes is an Associate of the Royal College of Science. 

Areas of Practice

• Intellectual Property

Education

• Fordham University School of Law, 2008
  J.D. Candidate
• Imperial College London, 1996
  Ph.D.
  Major: Biology
• Imperial College London, 1992
  B.Sc.
  Honors: First Class Honors
  Major: Biology

Published Works

• Comparative studies of intracellular calcium in strongly and weakly metastatic rat prostate cancer cell lines, 2006
• Predominant expression of Kv1.3 voltage-gated K+ channel subunit in rat prostate cancer cell line: electrophysiological, pharmacological and molecular characterization, 2003
• Effects of voltage-gated ion channel modulators on rat prostatic cancer cell proliferation: Comparison of highly and weakly metastatic cell lines, 2000
• The co-repressor mSin3A is a functional component of the REST/CoREST repressor complex, 2000
• CoREST: A functional co-repressor required for regulation of neural-specific gene expression, 1999
• Electrophysiological characterization of a voltage-gated Na+ current expressed in the highly metastatic Mat-LyLu rat prostate cancer cell line, 1998
• Expression and functional analysis of voltage-activated Na+ channels in human prostate cancer cell lines and their contribution to invasion in vitro, 1997
• Voltage-gated K+ current in the highly metastatic MAT-LyLu rat prostate cancer cell line: Electrophysiological and pharmacological characteristics, 1996
• Electrophysiological characterization of a TTX-sensitive Na+ current in the highly metastatic MAT-LyLu rat prostate cancer cell line, 1995
• Differential expression of voltage-activated Na+ currents in two prostatic tumour cell lines: Contribution to invasiveness in vitro, 1995

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New York, NY 10022

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Websites

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